The Cytocybernetics AC4x4 Artificial Cell The Cytocybernetics AC4x4 is a switchable artificial electronic cell for use with voltage clamp amplifiers. This artificial cell is specifically designed for use with stem cell derived cell types (including iPSCD cardiac cells) which may have a very high background resistance and highly variable cell capacitances.
The AC4x4 implements an equivalent cell for whole cell measurements. The internal components consist of: - four selectable series resistances (electrode equivalent) - four selectable cell capacitances with a 5 GΩ shunt (membrane seal equivalent).
The switch settings allow for 15 possible different electrode resistances and 15 different membrane capacitances for a total of over 200 possible configurations.
The AC4x4 has many uses: Testing equipment. Debugging system noise. Adjusting headstage bias currents. Teaching students the basics of patch clamp. Determining stable operating configurations for dynamic clamp and current clamp applications.
The AC4x4 uses high precision selectable components for reproducible and reliable capacitive transients:
The user can select over 200 possible combinations. If you require a special combination, we can create a custom artificial cell to meet your needs. Contact us at: email@example.com